An introductory course focusing on the chemistry of naturally occurring and synthetic carbon compounds; description and determination of structure with an emphasis on spectroscopic methods; reactivity and its theoretical basis; mechanism; and synthesis of organic compounds. The microscale laboratory emphasizes preparation, purification and identification of organic compounds, isolation of organic substances, mechanistic studies and separation techniques. Spectroscopic methods are applied to structure elucidation. Prerequisites: CHEM104 with a grade of 2.0 or higher. Acceptance into 222 requires a grade of 2.0 or higher in 221. CHEM 221 is required for the neuroscience major.